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DNA testing or deeper blood work?

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13 years 1 month ago #31257 by Stoic
DNA testing or deeper blood work? was created by Stoic
Was reading some internet info and someone mentioned DNA testing to check for mutated genes? I don't even know what I am talking about but has anybody tried this or know anything about it? :dry:

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13 years 1 month ago #31259 by 2Jacks
Replied by 2Jacks on topic DNA testing or deeper blood work?
I'm wondering about the same thing. Also, is it available in Canada or just the US?

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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13 years 1 month ago #31265 by Sandi
Replied by Sandi on topic DNA testing or deeper blood work?
Here is some info about that.


www.ncbi.nlm.nih.gov/pmc/articles/PMC3461273/


Just a question - what purpose do you think it would serve to test your DNA?

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13 years 1 month ago #31266 by eklein
Replied by eklein on topic DNA testing or deeper blood work?
I think one day DNA testing would reveal which treatments would be effective or ineffective. Not yet though But with many cancers we are at the point where DNA testing can indicate which treatments to pursue or not.
Erica

And she was!
Diagnosed May 2005, lowest count 8K.
4/22/08: 43K (2nd Rituxan)
10/01/09: 246K, 1/8/10: 111K, 5/21/10: 233K
Latest count: 7/27/2015: 194K

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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13 years 1 month ago #31274 by Sandi
Replied by Sandi on topic DNA testing or deeper blood work?
Exactly, but it doesn't help now. So far, nothing determines which treatments will be effective. If they could only get that part figured out....

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13 years 1 month ago #31289 by Stoic
Replied by Stoic on topic DNA testing or deeper blood work?
I was thinking of genetic mutations that would predispose someone to certain illnesses....Like if a certain chromosome had a bad whatever in it and no matter what I do we are just going to have to deal with this because there is no hope. Why keep trying then? And why not just wait for death? Why continue to let this thing drain any extra funds I have. Why be a beggar in my family? :unsure:

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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13 years 1 month ago #31397 by Sandi
Replied by Sandi on topic DNA testing or deeper blood work?
I'm not quite sure what you mean up there. Please explain.

I found this today:

MicroRNA are small noncoding RNA molecules that regulate gene expression. To investigate the role of microRNA in immune thrombocytopenia (ITP), we performed genome-wide expression analyses of mRNA and microRNA in T cells from ITP patients and controls. We identified 1915 regulated genes and 22 regulated microRNA that differed between ITP patients and controls. Seventeen of the 22 regulated microRNA were linked to changes in target gene expression; 57 of these target genes were associated with the immune system, eg, T-cell activation and regulation of immunoglobulin production. CXCL13 and IL-21 were two microRNA target genes significantly increased in ITP. We could demonstrate increased plasma levels of CXCL13 and others have reported increased plasma levels of interleukin-21 in ITP. Thus, regulated microRNA were significantly associated with both gene and protein expression of molecules in immunological pathways. We suggest that microRNA may be important regulatory molecules involved in the loss of tolerance in ITP.

bloodjournal.hematologylibrary.org/content/121/11/2095.abstract?ct

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13 years 1 month ago #31403 by Stoic
Replied by Stoic on topic DNA testing or deeper blood work?
The article you posted is what I was thinking of. I needed to know if there was a way to dig deeper. It appears there is but no conclusive evidence to say "your case is hopeless" Just have to keep plodding along.

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  • Sandi
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  • Sandi Forum Moderator Diagnosed in 1998, currently in remission. Diagnosed with Lupus in 2006. Last Count - 344k - 6-9-18
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13 years 1 month ago #31417 by Sandi
Replied by Sandi on topic DNA testing or deeper blood work?
I don't think any case is hopeless. Some may be very difficult, but even at that I've seen many of those people lead normal lives.

Plodding along is about it. You do the best you can.

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13 years 1 month ago #31586 by Stoic
Replied by Stoic on topic DNA testing or deeper blood work?
Jesus came through.....After 2 years we just went in and her platlets are at 98,000 after our last treatment.........................

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