Platelet Disorder Support Association

Join Us:

Become a Member

Support Us:

Make a Donation
    Remember Me     Forgot Login?   Sign up   •  Web site Help & Info
!!! DISCUSSION GROUP RULES !!!

1. You must be a registered website user in order to post and comment. Guests may read only.
2. Be kind and helpful, not rude and cynical.
3. Don't advertise or promote anything. You will be banned from the group.
4. Report problems to the moderators. THANK YOU!

RUNX1

More
10 years 2 weeks ago #51250 by lmayes
RUNX1 was created by lmayes
Can someone please explain RUNX1 in laymans terms? I was just diagnosed after 19 years of believing to just have ITP. What is next step as far as treatment for a 21 year old female? What should I expect with this new diagnosis?
More
10 years 2 weeks ago #51251 by Ann
Replied by Ann on topic RUNX1
What exactly is the diagnosis. Is it a RUNX1 deficiency or a disease caused by a mutation? Having said that I only know what google can tell me and I expect you've done that already.
More
10 years 2 weeks ago #51252 by lmayes
Replied by lmayes on topic RUNX1
It's "familial platelet disorder with predisposition to AML" and I googled my heart out but it gave me absolutely nothing that made any sense.
More
10 years 2 weeks ago #51253 by Ann
Replied by Ann on topic RUNX1
Ah, so you are one of those with a familial thrombocytopenia misdiagnosed as ITP. We have seen a few of those here. Usually it's obvious when the person says that a family member or two also have low counts. So now they are just studying what the defects are. The best explanation I found in a respected journal is here..

www.bloodjournal.org/content/122/25/4004?sso-checked=true
More
10 years 2 weeks ago #51256 by Aoi
Replied by Aoi on topic RUNX1
Sorry to hear about your diagnosis. Some useful information can be found in the OMIM database at

omim.org/entry/601399?search=runx1&highlight=runx1

This should provide a useful overview of the disorder, with lots of links to further research.
Platelet Disorder Support Association

Donate

About

Stay Informed

Follow Us

IMPORTANT!

The Platelet Disorder Support Association does not provide medical advice or endorse any medication, vitamins or herbs. The information contained herein is not intended nor implied to be a substitute for professional medical advice and is provided for educational purposes only. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment, discontinuing an existing treatment and to discuss any questions you may have regarding your unique medical condition.


Platelet Disorder Support Association
8751 Brecksville Road, Suite 150, Cleveland, Ohio 44141
Phone: 1-87-PLATELET | 877-528-3538 (toll free) | or 440-746-9003
E-mail: pdsa@pdsa.org


© Copyright 1997 - 2025, Platelet Disorder Support Association. All rights reserved.
The Platelet Disorder Support Association is a 501(c)3 organization and donations are tax deductible to the fullest extent allowed by law.


Privacy Policy and Terms of Use